Highest development stage: Preclinical

Development dropped

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Protein synthesis inhibitors; improved potency against Gram positive bacteria and fastidious Gram negative compared with linezolid

Additional information: Renslo AR, Gao H, Jaishankar P, et al. Synthesis and antimicrobial activity of novel oxa-, aza-, and thiabicyclo[3.1.0]hexylphenyl oxazolidinone analogs. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;19