Highest development stage: Preclinical

Development dropped

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: 50S ribosomal subunit inhibitor; this series generally showed lower MICS against S. aureus and enterococcal isolates

Additional information: Lawrence L, Sutcliffe J. In vitro activity of designer oxazolidinones against respiratory pathogens. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;198.