Development status: Inactive

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Inhibits RNA polymerase. Broad Spectrum but more potent against Gram positives. Specifically active against Mycobacteria(2)

Reason dropped: Demonstrates partial cross resistance with rifamycins due to partial overlap in binding site but has ' potential promise as an antituberculosis agent effective against a subset of rifamycin-resistant bacterial infections' (2)