Highest development stage: Preclinical

Development dropped

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Broad Spectrum against Aerobic and Anaerobic bacteria (2)

Reason dropped: Unstable at different pH's and easily oxidated (1). Additionally, little in vivo activity in mice model when administered subcutaneously but was effective through intraperitoneal injection suggesting metabolism of compound and hence preventing its transloction to site of infection (2).

Additional information: macrocyclic polyene lactone phosphate ester