Highest development stage: Phase 3

Development dropped

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Demonstrated very fast bactericidal activity against S. aureus. Tested against oral mucositis, at concentrations of 0.12, 0.5 and 2 mg/ml, resulted in reduction of microflora density

Additional information: Loury DJ, Embree J, So W, et al. Topical administration of IB-367, a novel antimicrobial peptide, reduced the severity of oral mucositis, in 5-FU-treated hamsters. 38th-Intersci-Conf-Antimicrobial-Agents-Chemother 1998; 277.