Highest development stage: Phase 1

Development dropped

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Ro 40-6890 is a broad spectrum antibiotic. The MIC(90) value against MSSA is 1mg/L and for E. coli 0.12mg/L.

Additional information: Hubschwerlen C, Charnas R, Angehrn P, et al. Ro 41-3399, a new oral Cephalosporin ester: synthesis and sructure- activity relations. 32nd-Intersci-Conf-Antimicrobial-Agents-Chemother 1992; 142