Highest development stage: Phase 2

Development dropped

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Cell wall inhibitor; was in clinical trials for Gram positive infections

Reason dropped: Adverse effects (S1, 1)

Additional information: Young CL, Rusca A, Di Stefano AFD, Radicioni M, Binelli D, Loprete L, et al. Safety and multiple dose pharmacokinetics of intravenous PZ-601 (SMP-601): a novel carbapenem. 47th-ICAAC-2007 2007;9-10