AntibioticDB

Highest development stage: Preclinical

Development active

Gram-positive activity

Gram-negative activity

Combination therapy

Mechanism of Action/Target pathogen: The 1:1 hBD-1/hBD-2 combination showed maximum effectiveness against varying gram negative and positive bacterium including E. coli, S. aureus,S. Typhi and S. enterica

GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3648

Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249419/

Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/163297647

hBD-2

Antimicrobial peptide

Division of Gene Function and Regulation, Institute of Life Sciences, Department of Biotechnology, Government of India, Bhubaneswar, Odisha, India

1999