Development status: Experimental

Gram-negative activity

Mechanism of Action/Target pathogen: Active against Escherichia coli; restores activity of beta-lactams in Enterobacterales

Additional information: Synthetic compound; active moiety of the prodrug ETX0282; tested in combination with cefpodoxime, does not inhibit VIM-1 or NDM-1; also inhibits PBP2 of Enterobacterales