Development status: Approved, off-patent, not available in most countries

Gram-positive activity

Mechanism of Action/Target pathogen: Binds to bacterial penicillin-binding protein 2 (PBP2) and interferes with bacterial cell wall integrity and synthesis. Active against Gram-positive bacteria, but vulnerable to penicillinases produced by staphylococci

Additional information: Semisynthetic penicillin, similar to ampicillin