Development status: Approved, off-patent, not available in most countries

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Binds to bacterial penicillin-binding proteins (PBP) and interferes with bacterial cell wall integrity and synthesis. Active against Gram-positive bacteria, but vulnerable to penicillinases produced by staphylococci and E. coli

Additional information: Semisynthetic penicillin, similar to penicillin V