Development status: Approved, off-patent, not available in most countries

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Binds to bacterial penicillin-binding proteins (PBP) and interferes with bacterial cell wall integrity and synthesis. Active against Gram-positive and some Gram-negative bacteria including Pseudomonas aeruginosa, but vulnerable to beta-lactamases

Additional information: Semisynthetic penicillin, derived from 6-aminopenicillanic acid (6-APA). Combination with clavulanic acid developed. Parenteral application