AntibioticDB

Tazobactam, YTR 830

Beta-lactamase inhibitor, penicillanic acid sulfone

1982

Development status: Approved, off-patent
Combination therapy
Mechanism of Action/Target pathogen: Binds irreversibly to beta-lactamases, mainly class A enzymes. No intrinsic antibacterial activity
Source: https://journals.asm.org/doi/epdf/10.1128/AAC.29.6.980
Citation (1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806661/
Citation (2): https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01279
Citation (3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179968/
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/Tazobactam