Development status: Approved, off-patent

Gram-negative activity

Mechanism of Action/Target pathogen: Inhibits protein synthesis by binding to the 30S subunit of the bacterial ribosome. Active against protozoa and some Gram-negative bacteria

Additional information: Streptomyces natural product. Veterinary use, human use for the treatment of cryptosporidiosis, leishmaniasis, amoebiasis and cestodes, systemic and topical application