AntibioticDB

Isepamicin

Aminoglycoside

1973

Development status: Approved, off-patent
Gram-negative activity
Mechanism of Action/Target pathogen: Inhibits protein synthesis by binding to the 30S subunit of the bacterial ribosome. Active against Gram-negative bacteria
Additional information: Semisynthetic, derived from gentamicin B
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=12136
Source: https://pubmed.ncbi.nlm.nih.gov/727766/
Citation (1): https://academic.oup.com/jac/article/44/1/99/750578
Citation (2): https://pubmed.ncbi.nlm.nih.gov/33610258/
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/3037209