Development status: Approved, off-patent

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Inhibits protein synthesis by binding to the 30S subunit of the bacterial ribosome. Active against Gram-positive and Gram-negative bacteria, mainly used against severe infections caused by Pseudomonas aeruginosa in combination

Additional information: Micromonospora natural product. Available in parenteral, enteral (selective decontamination) and topical formulations; veterinary and human use