Development status: Approved in Taiwan

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Nemonoxacin (TG-873870) is a novel non-fluorinated quinolone with potent broad-spectrum activity against gram-positive, gram-negative, and atypical pathogens, including vancomycin-nonsusceptible methicillin-resistant Staphylococcus aureus (MRSA), quinolone-resistant MRSA, quinolone-resistant Streptococcus pneumoniae, penicillin-resistant S. pneumoniae, and erythromycin-resistant S. pneumoniae.

Additional information: Cardiovascular Safety Evaluation of Nemonoxacin (TG-873870) in Dogs and Monkeys. . A-27. Abstr. 47th Intersci. Conf. Antimicrob. Agents Chemother.
By: Chow, C. P.; Tsai, C. Y.; Chen, Y. M.