AntibioticDB

Thioridazine

Phenothiazine

Novartis, Switzerland

Highest development stage: Discontinued
Gram-positive activity
Mechanism of Action/Target pathogen: MRSA. Has also shown to make MRSA sensitive to Beta-lactam antibiotics
Reason dropped: Caused severe cardiac arrhythmias
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=100
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203271/
Citation (1): https://aac.asm.org/content/64/7/e00181-20
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/5452