AntibioticDB

Ivermectin/Colistin

Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, University Hospital Virgen del Rocío, Seville, Spain. Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain., Sevilla, Spain, Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain. Department of Medicine, University of Seville, Seville, Spain., Sevilla, Spain

2019

Highest development stage: Preclinical
Development active
Gram-negative activity
Combination therapy
Mechanism of Action/Target pathogen: Antibacterial effect of colistin against Col-S and Col-R A. baumannii, P. aeruginosa and K. pneumoniae.
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2373
Source: https://www.eccmidlive.org/#!resources/in-vitro-activity-of-ivermectin-in-combination-with-colistin-against-gram-negative-bacilli-5b1695c5-cf06-4761-baee-d2ab3646d5c4
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/6427057
Compound/Drug Structure (2): https://pubchem.ncbi.nlm.nih.gov/compound/5311054