AntibioticDB

ETX0282CPDP (ETX0282 + cefpodoxime)

Beta-lactam (cephalosporin)

Entasis Therapeutics

Highest development stage: Phase 1
Development status: Active
Gram-negative activity
Combination therapy
Mechanism of Action/Target pathogen: Complicated UTIs (Enterobacteriaceaeincluding ESBL-producing and CRE)
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=10781
Source: https://www.medkoo.com/products/30174
Citation (1): http://www.entasistx.com/application/files/6815/1846/7209/ODonnell-et-al-ASM-Microbe-2017-SAT-278.pdf
Citation (2): http://www.entasistx.com/pipeline
Compound/Drug Structure (2): https://pubchem.ncbi.nlm.nih.gov/compound/6335986#section=3D-Conformer